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Contact details

drawing Ines Simeone ines.simeone@iit.it

drawing Francesco Nicassio francesco.nicassio@iit.it

drawing Luigi Cerulo luigi.cerulo@unisannio.it

Our publications on miRNA degradation and/or TDMD

Ghini, F., Rubolino, C., Climent, M., Simeone, I., Marzi, M. J., & Nicassio, F. (2018). Endogenous transcripts control miRNA levels and activity in mammalian cells by target-directed miRNA degradation. Nature communications, 9(1), 3119.
Marzi, M. J., Ghini, F., Cerruti, B., De Pretis, S., Bonetti, P., Giacomelli, C., … & Amati, B. (2016). Degradation dynamics of microRNAs revealed by a novel pulse-chase approach. Genome research, gr-198788.

Our softwares for non coding RNA research

drawing islnc is a tool to recognize novel long non coding transcripts from sequence data and/or genome coordinates in gtf format.

drawing Isomirage is a desktop application that determines the occurrence of different miRNA isoforms based on NGS data.